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The Human Brain Atlas project
The goal of the Human Brain Atlas project is to provide public access to a large
collection of high-quality histological gene expression data from the developing
human brain. In the first stage of this project, we have surveyed gene expression
in the human brain during the late second trimester, using Affymetrix Human Exon
Arrays and tissue samples microdissected from more than 20 regions of four brains.
Although the centerpiece of this project will be
high-quality, cellular-resolution images of in situ hybridization, immuno-, and
histochemical stainings of developing human brain, we have also included microarray
expression data from this project, as well as a large amount of quantitative RT-PCR
data.
Supplemental Figures, Data, and Methods from the accompanying paper, "Functional and Evolutionary Insights Into Human Brain Development Through Global Transcriptome Analysis," Johnson et al., Neuron (2009),
are available from the About page.
We would like to alert visitors that the website is under construction. At this time, digitized histological images are available for the following genes. In the future, these and all other images will be annotated. You can view these images by following the links below and clicking on the "Images" tab. Quantitative RT-PCR data are also available for these and many more genes in the database, and can be viewed by clicking on the "Data Graphs" tab. If you would like more information please contact us. Thank you for visiting!